Table 1

Attenuated bacteria as vaccine vehicles
Vaccine strain	Attenuation	Foreign insert	Model	Ref.

Shigella flexneri	Δasd	pCMVβ	Guinea pig, in vitro	[80]
	Δasd	CS3 and LTB/STm	Mouse	[81]
	ΔrfbF	HIV-1 SF2Gag	Mouse	[17]
	ΔdapA ΔdapB	β-gal, gene vaccine	In vitro	[16]
	ΔaroA ΔiscA	gp120, gene vaccine	Mouse	[15]

Salmonella enterica	ΔaroA	pCMVβ, pCMVactA and pCMVhly	In vitro, mouse	[82]
	ΔaroA ΔaroD	C. tetani TTFC	Mouse	[83]
	ΔaroA ΔhtrA	TTFC	Mouse	[83]
	ΔaroA+others	GFP+cytokines	Mouse	[84]
	Δcya Δcrp Δasd	SP10 cDNA	Mouse	[20]
	GalE + unspecified	H. pylori, ureAB	Human	[85]

Yersinia enterocolitica	pYV^-	B. abortus, P39	Mouse	[86]
	pYV^-	Ova	Mouse	[87]

Listeria monocytogenes	ΔactA	Leichmania major	Mouse	[88]
	ΔactA	LCM virus	Mouse	[89]
	Δdal Δdat	HIV-1 gag gene vaccine	Mouse	[90]
	Δ2	M. bovis gene vaccine	Mouse	[91]

Bordetella bronhiseptica	ΔaroA	TTFC	Mouse	[92]

Erysipelotrix rhusiopatie	Tn916^-	M. hyopneumonie	Mouse, pig	[93]

Mycobacterium bovis	unspecified	P. falciparum, CSP	Mouse	[94]

Brucella abortus	Rough mutant (O^-)	lacZ or HSP65	Mouse	[95]

Detmer and Glenting Microbial Cell Factories 2006 5:23 doi:10.1186/1475-2859-5-23