Figure 8.

Metabolic pathway for GDP-fucose synthesis in Saccharomyces cerevisiae [17]. Enzymes – 1: GDP-mannose-4,6-dehydratase (Gmd), 2: GDP-4-keto-6-deoxy-mannose-3,5-epimerase (GmeR), 3: 4-reductase (GmeR), 4: GDP-fucose pyrophosphorylase, 5: fucose kinase.