Table 2

Gateway recombination cloning of 34 LUCA and ECHH genes

No.
Protein
Yield with His7-tag
Fusion with
Yield

157
aspartokinase I; homoserine dehydrogenase I
1
MBP
3
145
acetolactate synthase III small subunit
1
MBP
3
203
thiogalactoside acetyltransferase
1
MBP
2
200
4-hydroxy-2-ketovalerate aldolase
1
MBP
2
258
putative ATPase
1
MBP
3
204
anthranilate synthase component II
1
MBP
2
155
putative ATP-binding component of a transport system
1
MBP
3
201
flagellum-specific ATP synthase
1
MBP
2
259
fused enoyl-CoA hydratase and epimerase
1
MBP
2
156
FFh
1
MBP
2
146
30S ribosomal subunit protein S11
1
MBP
2
147
30S ribosomal subunit protein S13
1
MBP
3
148
50S ribosomal subunit protein L14
1
MBP
3
149
50S ribosomal subunit protein L22
1
MBP
3
151
50S ribosomal subunit protein L23
1
MBP
2
152
30S ribosomal subunit protein S12
1
MBP
2
150
50S ribosomal subunit protein L2
1
MBP
3
154
50S ribosomal subunit protein L1
1
MBP
3
153
biotin- [acetyl-CoA carboxylase] holoenzyme synthetase
1
MBP
3
159
RNA polymerase beta prime subunit
1
MBP
2
143
predicted acyltransferase with acyl-CoA N-acyltransferase
1
MBP
3
144
putative proteoglycan
1
MBP
2
158
endonuclease III
1
MBP
2
161
dihydroxyacid dehydratase
1
MBP
3
202
part of formate-dependent nitrite reductase complex
1
NusA
2
206
conserved protein, member of DEAD box family
1
NusA
2
198
50S ribosomal subunit protein L5
0
NusA
2
205
O-6-alkylguanine-DNA/cysteine-protein methyltransferase
0
NusA
1
199
acetylornithine delta-aminotransferase
0
NusA
1
197
inducible ATP-independent RNA helicase
1
GST
2
160
glutamate synthase large subunit
1

-
207
carbamoyl-phosphate synthase large subunit
1

-
208
ATP-binding transport protein (membrane protein)
0

-
209
Mg2+ transport ATPase, P-type 1 (membrane protein)
0

-

Yields of purified proteins were analyzed by SDS-PAGE before recombination (proteins fused to His7-tag) and after recombination (each target protein fused to MBP-His7, GST-His7, or NusA-His6, respectively). The fusion partner that most efficiently improved protein yield is shown. With regard to yield, proteins were attributed to one of four categories: 3 (high), 2 (moderate), 1 (low), 0 (not purified).

Ergin et al. Microbial Cell Factories 2007 6:18   doi:10.1186/1475-2859-6-18