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This trehalose synthase is the family GH13 member
Stefan Janecek (18 July 2009) Institute of Molecular Biology, Slovak Academy of Sciences, Bratislava, Slovakia
There is an error in this paper concerning the classification of the new trehalose synthase from Enterobacter hormaechei. The authors wrote their trehalose synthase belongs to the glycoside hydrolase family GH16 (the alignment shown in Figure 1), indicating also the essential residues. But it is clear that the sequence features (Fig. 1) are those of the family GH13 (the alpha-amylase family, forming the clan GH-H - the families GH13, GH70 and GH77). Obviously the authors ignored the key references, such as the sequence-based CAZy classification of GHs (http://www.cazy.org/) as well as the relevant reviews on the alpha-amylase family GH13 (clan GH-H) describing sequence/structure/function/evolution of these enzymes.
Competing interests
No competing interests.
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