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Open Access Highly Accessed Commentary

Open access to sequence: Browsing the Pichia pastoris genome

Diethard Mattanovich12*, Nico Callewaert34, Pierre Rouzé56, Yao-Cheng Lin56, Alexandra Graf12, Andreas Redl12, Petra Tiels34, Brigitte Gasser1 and Kristof De Schutter37

Author Affiliations

1 Department of Biotechnology, University of Natural Resources and Applied Life Sciences, Vienna, Austria

2 School of Bioengineering, University of Applied Sciences FH-Campus Wien, Vienna, Austria

3 Unit for Molecular Glycobiology, Department for Molecular Biomedical Research, VIB, Ghent-Zwijnaarde, Belgium

4 Unit for Molecular Glycobiology, L-ProBE, Department of Biochemistry and Microbiology, Ghent University, Ghent-Zwijnaarde, Belgium

5 Department of Plant Systems Biology, VIB, Ghent-Zwijnaarde, Belgium

6 Department of Plant Biotechnology and Genetics, Ghent University, Ghent, Belgium

7 Department for Biomedical Molecular Biology, Ghent University, Ghent-Zwijnaarde, Belgium

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Microbial Cell Factories 2009, 8:53  doi:10.1186/1475-2859-8-53

Published: 16 October 2009

Abstract

The first genome sequences of the important yeast protein production host Pichia pastoris have been released into the public domain this spring. In order to provide the scientific community easy and versatile access to the sequence, two web-sites have been installed as a resource for genomic sequence, gene and protein information for P. pastoris: A GBrowse based genome browser was set up at http://www.pichiagenome.org webcite and a genome portal with gene annotation and browsing functionality at http://bioinformatics.psb.ugent.be/webtools/bogas webcite. Both websites are offering information on gene annotation and function, regulation and structure.

In addition, a WiKi based platform allows all users to create additional information on genes, proteins, physiology and other items of P. pastoris research, so that the Pichia community can benefit from exchange of knowledge, data and materials.