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Systems biotechnology and metabolic engineering

Edited by: Prof Sang Yup Lee

Microbial Cell Factories invites submissions to this special thematic series on the topic of Systems biotechnology and metabolic engineering. It is now time to exploit systems approaches to microbial biotechnology, starting with up-stream (strain, cell and organism development) by metabolic engineering, which will ultimately lead to successful biotechnology development when combined with systems engineering of mid- to down-stream processes.

Please see here for further details, including how to submit your new work to the series.

Collection published: 7 February 2013

Last updated: 4 April 2013

		Research Reconstruction of the biosynthetic pathway for the core fungal polyketide scaffold rubrofusarin in Saccharomyces cerevisiae Peter Rugbjerg, Michael Naesby, Uffe H Mortensen, Rasmus JN Frandsen Microbial Cell Factories 2013, 12:31 (4 April 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
		Research The metabolic costs of improving ethanol yield by reducing glycerol formation capacity under anaerobic conditions in Saccharomyces cerevisiae Julien Pagliardini, Georg Hubmann, Sandrine Alfenore, Elke Nevoigt, Carine Bideaux, Stephane E Guillouet Microbial Cell Factories 2013, 12:29 (28 March 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
		Research Expression and functional studies of genes involved in transport and metabolism of glycerol in Pachysolen tannophilus Xiaoying Liu, Uffe Hasbro Mortensen, Mhairi Workman Microbial Cell Factories 2013, 12:27 (21 March 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
		Research A comparative analysis of the properties of regulated promoter systems commonly used for recombinant gene expression in Escherichia coli Simone Balzer, Veronika Kucharova, Judith Megerle, Rahmi Lale, Trygve Brautaset, Svein Valla Microbial Cell Factories 2013, 12:26 (18 March 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
		Research Optimizing heterologous protein production in the periplasm of E. coli by regulating gene expression levels Susan Schlegel, Edurne Rujas, Anders Jimmy Ytterberg, Roman A Zubarev, Joen Luirink, Jan-Willem de Gier Microbial Cell Factories 2013, 12:24 (12 March 2013) Abstract \| Full text \| PDF \| PubMed
		Research Genome-scale reconstruction and in silico analysis of Klebsiella oxytoca for 2,3-butanediol production Jong Myoung Park, Hyohak Song, Hee Jong Lee, Doyoung Seung Microbial Cell Factories 2013, 12:20 (23 February 2013) Abstract \| Full text \| PDF \| PubMed
		Research Improved production of secreted heterologous enzyme in Bacillus subtilis strain MGB874 via modification of glutamate metabolism and growth conditions Kenji Manabe, Yasushi Kageyama, Takuya Morimoto, Eri Shimizu, Hiroki Takahashi, Shigehiko Kanaya, Katsutoshi Ara, Katsuya Ozaki, Naotake Ogasawara Microbial Cell Factories 2013, 12:18 (18 February 2013) Abstract \| Full text \| PDF \| PubMed
		Research Efficient synthesis of L-lactic acid from glycerol by metabolically engineered Escherichia coli Suman Mazumdar, Matthew D Blankschien, James M Clomburg, Ramon Gonzalez Microbial Cell Factories 2013, 12:7 (25 January 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
		Research Engineering a cyanobacterium as the catalyst for the photosynthetic conversion of CO₂ to 1,2-propanediol Han Li, James C Liao Microbial Cell Factories 2013, 12:4 (22 January 2013) Abstract \| Full text \| PDF \| PubMed
		Research Genetic manipulation of longevity-related genes as a tool to regulate yeast life span and metabolite production during winemaking Helena Orozco, Emilia Matallana, Agustín Aranda Microbial Cell Factories 2013, 12:1 (2 January 2013) Abstract \| Full text \| PDF \| PubMed
		Research Positive genetic interactors of HMG2 identify a new set of genetic perturbations for improving sesquiterpene production in Saccharomyces cerevisiae Codruta Ignea, Fotini A Trikka, Ioannis Kourtzelis, Anagnostis Argiriou, Angelos K Kanellis, Sotirios C Kampranis, Antonios M Makris Microbial Cell Factories 2012, 11:162 (22 December 2012) Abstract \| Full text \| PDF \| PubMed
		Editorial Systems metabolic engineering, industrial biotechnology and microbial cell factories Sang Yup Lee, Diethard Mattanovich, Antonio Villaverde Microbial Cell Factories 2012, 11:156 (11 December 2012) Abstract \| Full text \| PDF \| PubMed
		Research De novo production of the flavonoid naringenin in engineered Saccharomyces cerevisiae Frank Koopman, Jules Beekwilder, Barbara Crimi, Adele van Houwelingen, Robert D Hall, Dirk Bosch, Antonius JA van Maris, Jack T Pronk, Jean-Marc Daran Microbial Cell Factories 2012, 11:155 (8 December 2012) Abstract \| Full text \| PDF \| PubMed
		Research Artificial biosynthesis of phenylpropanoic acids in a tyrosine overproducing Escherichia coli strain Sun-Young Kang, Oksik Choi, Jae Lee, Bang Hwang, Tai-Boong Uhm, Young-Soo Hong Microbial Cell Factories 2012, 11:153 (3 December 2012) Abstract \| Full text \| PDF \| PubMed
		Research Adaptative biochemical pathways and regulatory networks in Klebsiella oxytoca BAS-10 producing a biotechnologically relevant exopolysaccharide during Fe(III)-citrate fermentation Giuseppe Gallo, Franco Baldi, Giovanni Renzone, Michele Gallo, Antonio Cordaro, Andrea Scaloni, Anna Puglia Microbial Cell Factories 2012, 11:152 (23 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research Rationally re-designed mutation of NAD-independent l-lactate dehydrogenase: high optical resolution of racemic mandelic acid by the engineered Escherichia coli Tianyi Jiang, Chao Gao, Peipei Dou, Cuiqing Ma, Jian Kong, Ping Xu Microbial Cell Factories 2012, 11:151 (23 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research Enhancing solubility of deoxyxylulose phosphate pathway enzymes for microbial isoprenoid production Kang Zhou, Ruiyang Zou, Gregory Stephanopoulos, Heng-Phon Too Microbial Cell Factories 2012, 11:148 (14 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research Design and testing of a synthetic biology framework for genetic engineering of Corynebacterium glutamicum Pablo Ravasi, Salvador Peiru, Hugo Gramajo, Hugo G Menzella Microbial Cell Factories 2012, 11:147 (7 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research Modulation of endogenous pathways enhances bioethanol yield and productivity in Escherichia coli Neha Munjal, Anu Jose Mattam, Dibyajyoti Pramanik, Prem Shankar Srivastava, Syed Yazdani Microbial Cell Factories 2012, 11:145 (4 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research In vivo modification of tyrosine residues in recombinant mussel adhesive protein by tyrosinase co-expression in Escherichia coli Yoo Choi, Yun Yang, Byeongseon Yang, Hyung Cha Microbial Cell Factories 2012, 11:139 (24 October 2012) Abstract \| Full text \| PDF \| PubMed
		Research Metabolic engineering of the purine biosynthetic pathway in Corynebacterium glutamicum results in increased intracellular pool sizes of IMP and hypoxanthine Susanne Peifer, Tobias Barduhn, Sarah Zimmet, Dietrich A Volmer, Elmar Heinzle, Konstantin Schneider Microbial Cell Factories 2012, 11:138 (24 October 2012) Abstract \| Full text \| PDF \| PubMed
		Research Novel polyoxins generated by heterologously expressing polyoxin biosynthetic gene cluster in the sanN inactivated mutant of Streptomyces ansochromogenes Jine Li, Lei Li, Chi Feng, Yihua Chen, Huarong Tan Microbial Cell Factories 2012, 11:135 (8 October 2012) Abstract \| Full text \| PDF \| PubMed
		Research Engineering Escherichia coli to increase plasmid DNA production in high cell-density cultivations in batch mode Gheorghe M Borja, Eugenio Meza Mora, Blanca Barrón, Guillermo Gosset, Octavio T Ramírez, Alvaro R Lara Microbial Cell Factories 2012, 11:132 (19 September 2012) Abstract \| Full text \| PDF \| PubMed
		Research An internal deletion in MTH1 enables growth on glucose of pyruvate-decarboxylase negative, non-fermentative Saccharomyces cerevisiae Bart Oud, Carmen-Lisset Flores, Carlos Gancedo, Xiuying Zhang, Joshua Trueheart, Jean-Marc Daran, Jack T Pronk, Antonius JA van Maris Microbial Cell Factories 2012, 11:131 (15 September 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research Production of copolyesters of 3-hydroxybutyrate and medium-chain-length 3-hydroxyalkanoates by E. coli containing an optimized PHA synthase gene Xue Gao, Xiao-Xi Yuan, Zhen-Yu Shi, Ying-Ying Guo, Xiao-Wen Shen, Jin-Chun Chen, Qiong Wu, Guo-Qiang Chen Microbial Cell Factories 2012, 11:130 (14 September 2012) Abstract \| Full text \| PDF \| PubMed
		Research Consequences of phosphoenolpyruvate:sugar phosphotranferase system and pyruvate kinase isozymes inactivation in central carbon metabolism flux distribution in Escherichia coli Eugenio Meza, Judith Becker, Francisco Bolivar, Guillermo Gosset, Christoph Wittmann Microbial Cell Factories 2012, 11:127 (13 September 2012) Abstract \| Full text \| PDF \| PubMed
		Research Extensive exometabolome analysis reveals extended overflow metabolism in various microorganisms Nicole Paczia, Anke Nilgen, Tobias Lehmann, Jochem Gätgens, Wolfgang Wiechert, Stephan Noack Microbial Cell Factories 2012, 11:122 (11 September 2012) Abstract \| Full text \| PDF \| PubMed
		Research Synthetic metabolic engineering-a novel, simple technology for designing a chimeric metabolic pathway Xiaoting Ye, Kohsuke Honda, Takaaki Sakai, Kenji Okano, Takeshi Omasa, Ryuichi Hirota, Akio Kuroda, Hisao Ohtake Microbial Cell Factories 2012, 11:120 (6 September 2012) Abstract \| Full text \| PDF \| PubMed
		Research Combined metabolic engineering of precursor and co-factor supply to increase α-santalene production by Saccharomyces cerevisiae Gionata Scalcinati, Siavash Partow, Verena Siewers, Michel Schalk, Laurent Daviet, Jens Nielsen Microbial Cell Factories 2012, 11:117 (31 August 2012) Abstract \| Full text \| PDF \| PubMed
		Technical Notes A genetic replacement system for selection-based engineering of essential proteins Sonja Billerbeck, Sven Panke Microbial Cell Factories 2012, 11:110 (16 August 2012) Abstract \| Full text \| PDF \| PubMed
		Research Rational improvement of the engineered isobutanol-producing Bacillus subtilis by elementary mode analysis Shanshan Li, Di Huang, Yong Li, Jianping Wen, Xiaoqiang Jia Microbial Cell Factories 2012, 11:101 (3 August 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research Increased expression of the yeast multidrug resistance ABC transporter Pdr18 leads to increased ethanol tolerance and ethanol production in high gravity alcoholic fermentation Miguel C Teixeira, Cláudia P Godinho, Tânia R Cabrito, Nuno P Mira, Isabel Sá-Correia Microbial Cell Factories 2012, 11:98 (27 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Review Microalgal biofactories: a promising approach towards sustainable omega-3 fatty acid production T Adarme-Vega, David K Y Lim, Matthew Timmins, Felicitas Vernen, Yan Li, Peer M Schenk Microbial Cell Factories 2012, 11:96 (25 July 2012) Abstract \| Full text \| PDF \| PubMed
		Research Biocatalytic synthesis of flavones and hydroxyl-small molecules by recombinant Escherichia coli cells expressing the cyanobacterial CYP110E1 gene Takuya Makino, Toshihiko Otomatsu, Kazutoshi Shindo, Emi Kitamura, Gerhard Sandmann, Hisashi Harada, Norihiko Misawa Microbial Cell Factories 2012, 11:95 (18 July 2012) Abstract \| Full text \| PDF \| PubMed
		Research An inverse metabolic engineering approach for the design of an improved host platform for over-expression of recombinant proteins in Escherichia coli Chaitali Ghosh, Rashmi Gupta, Krishna Mukherjee Microbial Cell Factories 2012, 11:93 (3 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central

		Research Reconstruction of the biosynthetic pathway for the core fungal polyketide scaffold rubrofusarin in Saccharomyces cerevisiae Peter Rugbjerg, Michael Naesby, Uffe H Mortensen, Rasmus JN Frandsen Microbial Cell Factories 2013, 12:31 (4 April 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
		Research The metabolic costs of improving ethanol yield by reducing glycerol formation capacity under anaerobic conditions in Saccharomyces cerevisiae Julien Pagliardini, Georg Hubmann, Sandrine Alfenore, Elke Nevoigt, Carine Bideaux, Stephane E Guillouet Microbial Cell Factories 2013, 12:29 (28 March 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
		Research Expression and functional studies of genes involved in transport and metabolism of glycerol in Pachysolen tannophilus Xiaoying Liu, Uffe Hasbro Mortensen, Mhairi Workman Microbial Cell Factories 2013, 12:27 (21 March 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
		Research A comparative analysis of the properties of regulated promoter systems commonly used for recombinant gene expression in Escherichia coli Simone Balzer, Veronika Kucharova, Judith Megerle, Rahmi Lale, Trygve Brautaset, Svein Valla Microbial Cell Factories 2013, 12:26 (18 March 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
		Research Optimizing heterologous protein production in the periplasm of E. coli by regulating gene expression levels Susan Schlegel, Edurne Rujas, Anders Jimmy Ytterberg, Roman A Zubarev, Joen Luirink, Jan-Willem de Gier Microbial Cell Factories 2013, 12:24 (12 March 2013) Abstract \| Full text \| PDF \| PubMed
		Research Genome-scale reconstruction and in silico analysis of Klebsiella oxytoca for 2,3-butanediol production Jong Myoung Park, Hyohak Song, Hee Jong Lee, Doyoung Seung Microbial Cell Factories 2013, 12:20 (23 February 2013) Abstract \| Full text \| PDF \| PubMed
		Research Improved production of secreted heterologous enzyme in Bacillus subtilis strain MGB874 via modification of glutamate metabolism and growth conditions Kenji Manabe, Yasushi Kageyama, Takuya Morimoto, Eri Shimizu, Hiroki Takahashi, Shigehiko Kanaya, Katsutoshi Ara, Katsuya Ozaki, Naotake Ogasawara Microbial Cell Factories 2013, 12:18 (18 February 2013) Abstract \| Full text \| PDF \| PubMed
		Research Efficient synthesis of L-lactic acid from glycerol by metabolically engineered Escherichia coli Suman Mazumdar, Matthew D Blankschien, James M Clomburg, Ramon Gonzalez Microbial Cell Factories 2013, 12:7 (25 January 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
		Research Engineering a cyanobacterium as the catalyst for the photosynthetic conversion of CO₂ to 1,2-propanediol Han Li, James C Liao Microbial Cell Factories 2013, 12:4 (22 January 2013) Abstract \| Full text \| PDF \| PubMed
		Research Genetic manipulation of longevity-related genes as a tool to regulate yeast life span and metabolite production during winemaking Helena Orozco, Emilia Matallana, Agustín Aranda Microbial Cell Factories 2013, 12:1 (2 January 2013) Abstract \| Full text \| PDF \| PubMed
		Research Positive genetic interactors of HMG2 identify a new set of genetic perturbations for improving sesquiterpene production in Saccharomyces cerevisiae Codruta Ignea, Fotini A Trikka, Ioannis Kourtzelis, Anagnostis Argiriou, Angelos K Kanellis, Sotirios C Kampranis, Antonios M Makris Microbial Cell Factories 2012, 11:162 (22 December 2012) Abstract \| Full text \| PDF \| PubMed
		Editorial Systems metabolic engineering, industrial biotechnology and microbial cell factories Sang Yup Lee, Diethard Mattanovich, Antonio Villaverde Microbial Cell Factories 2012, 11:156 (11 December 2012) Abstract \| Full text \| PDF \| PubMed
		Research De novo production of the flavonoid naringenin in engineered Saccharomyces cerevisiae Frank Koopman, Jules Beekwilder, Barbara Crimi, Adele van Houwelingen, Robert D Hall, Dirk Bosch, Antonius JA van Maris, Jack T Pronk, Jean-Marc Daran Microbial Cell Factories 2012, 11:155 (8 December 2012) Abstract \| Full text \| PDF \| PubMed
		Research Artificial biosynthesis of phenylpropanoic acids in a tyrosine overproducing Escherichia coli strain Sun-Young Kang, Oksik Choi, Jae Lee, Bang Hwang, Tai-Boong Uhm, Young-Soo Hong Microbial Cell Factories 2012, 11:153 (3 December 2012) Abstract \| Full text \| PDF \| PubMed
		Research Adaptative biochemical pathways and regulatory networks in Klebsiella oxytoca BAS-10 producing a biotechnologically relevant exopolysaccharide during Fe(III)-citrate fermentation Giuseppe Gallo, Franco Baldi, Giovanni Renzone, Michele Gallo, Antonio Cordaro, Andrea Scaloni, Anna Puglia Microbial Cell Factories 2012, 11:152 (23 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research Rationally re-designed mutation of NAD-independent l-lactate dehydrogenase: high optical resolution of racemic mandelic acid by the engineered Escherichia coli Tianyi Jiang, Chao Gao, Peipei Dou, Cuiqing Ma, Jian Kong, Ping Xu Microbial Cell Factories 2012, 11:151 (23 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research Enhancing solubility of deoxyxylulose phosphate pathway enzymes for microbial isoprenoid production Kang Zhou, Ruiyang Zou, Gregory Stephanopoulos, Heng-Phon Too Microbial Cell Factories 2012, 11:148 (14 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research Design and testing of a synthetic biology framework for genetic engineering of Corynebacterium glutamicum Pablo Ravasi, Salvador Peiru, Hugo Gramajo, Hugo G Menzella Microbial Cell Factories 2012, 11:147 (7 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research Modulation of endogenous pathways enhances bioethanol yield and productivity in Escherichia coli Neha Munjal, Anu Jose Mattam, Dibyajyoti Pramanik, Prem Shankar Srivastava, Syed Yazdani Microbial Cell Factories 2012, 11:145 (4 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research In vivo modification of tyrosine residues in recombinant mussel adhesive protein by tyrosinase co-expression in Escherichia coli Yoo Choi, Yun Yang, Byeongseon Yang, Hyung Cha Microbial Cell Factories 2012, 11:139 (24 October 2012) Abstract \| Full text \| PDF \| PubMed
		Research Metabolic engineering of the purine biosynthetic pathway in Corynebacterium glutamicum results in increased intracellular pool sizes of IMP and hypoxanthine Susanne Peifer, Tobias Barduhn, Sarah Zimmet, Dietrich A Volmer, Elmar Heinzle, Konstantin Schneider Microbial Cell Factories 2012, 11:138 (24 October 2012) Abstract \| Full text \| PDF \| PubMed
		Research Novel polyoxins generated by heterologously expressing polyoxin biosynthetic gene cluster in the sanN inactivated mutant of Streptomyces ansochromogenes Jine Li, Lei Li, Chi Feng, Yihua Chen, Huarong Tan Microbial Cell Factories 2012, 11:135 (8 October 2012) Abstract \| Full text \| PDF \| PubMed
		Research Engineering Escherichia coli to increase plasmid DNA production in high cell-density cultivations in batch mode Gheorghe M Borja, Eugenio Meza Mora, Blanca Barrón, Guillermo Gosset, Octavio T Ramírez, Alvaro R Lara Microbial Cell Factories 2012, 11:132 (19 September 2012) Abstract \| Full text \| PDF \| PubMed
		Research An internal deletion in MTH1 enables growth on glucose of pyruvate-decarboxylase negative, non-fermentative Saccharomyces cerevisiae Bart Oud, Carmen-Lisset Flores, Carlos Gancedo, Xiuying Zhang, Joshua Trueheart, Jean-Marc Daran, Jack T Pronk, Antonius JA van Maris Microbial Cell Factories 2012, 11:131 (15 September 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research Production of copolyesters of 3-hydroxybutyrate and medium-chain-length 3-hydroxyalkanoates by E. coli containing an optimized PHA synthase gene Xue Gao, Xiao-Xi Yuan, Zhen-Yu Shi, Ying-Ying Guo, Xiao-Wen Shen, Jin-Chun Chen, Qiong Wu, Guo-Qiang Chen Microbial Cell Factories 2012, 11:130 (14 September 2012) Abstract \| Full text \| PDF \| PubMed
		Research Consequences of phosphoenolpyruvate:sugar phosphotranferase system and pyruvate kinase isozymes inactivation in central carbon metabolism flux distribution in Escherichia coli Eugenio Meza, Judith Becker, Francisco Bolivar, Guillermo Gosset, Christoph Wittmann Microbial Cell Factories 2012, 11:127 (13 September 2012) Abstract \| Full text \| PDF \| PubMed
		Research Extensive exometabolome analysis reveals extended overflow metabolism in various microorganisms Nicole Paczia, Anke Nilgen, Tobias Lehmann, Jochem Gätgens, Wolfgang Wiechert, Stephan Noack Microbial Cell Factories 2012, 11:122 (11 September 2012) Abstract \| Full text \| PDF \| PubMed
		Research Synthetic metabolic engineering-a novel, simple technology for designing a chimeric metabolic pathway Xiaoting Ye, Kohsuke Honda, Takaaki Sakai, Kenji Okano, Takeshi Omasa, Ryuichi Hirota, Akio Kuroda, Hisao Ohtake Microbial Cell Factories 2012, 11:120 (6 September 2012) Abstract \| Full text \| PDF \| PubMed
		Research Combined metabolic engineering of precursor and co-factor supply to increase α-santalene production by Saccharomyces cerevisiae Gionata Scalcinati, Siavash Partow, Verena Siewers, Michel Schalk, Laurent Daviet, Jens Nielsen Microbial Cell Factories 2012, 11:117 (31 August 2012) Abstract \| Full text \| PDF \| PubMed
		Technical Notes A genetic replacement system for selection-based engineering of essential proteins Sonja Billerbeck, Sven Panke Microbial Cell Factories 2012, 11:110 (16 August 2012) Abstract \| Full text \| PDF \| PubMed
		Research Rational improvement of the engineered isobutanol-producing Bacillus subtilis by elementary mode analysis Shanshan Li, Di Huang, Yong Li, Jianping Wen, Xiaoqiang Jia Microbial Cell Factories 2012, 11:101 (3 August 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research Increased expression of the yeast multidrug resistance ABC transporter Pdr18 leads to increased ethanol tolerance and ethanol production in high gravity alcoholic fermentation Miguel C Teixeira, Cláudia P Godinho, Tânia R Cabrito, Nuno P Mira, Isabel Sá-Correia Microbial Cell Factories 2012, 11:98 (27 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Review Microalgal biofactories: a promising approach towards sustainable omega-3 fatty acid production T Adarme-Vega, David K Y Lim, Matthew Timmins, Felicitas Vernen, Yan Li, Peer M Schenk Microbial Cell Factories 2012, 11:96 (25 July 2012) Abstract \| Full text \| PDF \| PubMed
		Research Biocatalytic synthesis of flavones and hydroxyl-small molecules by recombinant Escherichia coli cells expressing the cyanobacterial CYP110E1 gene Takuya Makino, Toshihiko Otomatsu, Kazutoshi Shindo, Emi Kitamura, Gerhard Sandmann, Hisashi Harada, Norihiko Misawa Microbial Cell Factories 2012, 11:95 (18 July 2012) Abstract \| Full text \| PDF \| PubMed
		Research An inverse metabolic engineering approach for the design of an improved host platform for over-expression of recombinant proteins in Escherichia coli Chaitali Ghosh, Rashmi Gupta, Krishna Mukherjee Microbial Cell Factories 2012, 11:93 (3 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central